The breast/uterine cancer study with no women invited

Dr. Ruth Simkin once wrote, in an editorial entitled Women’s Health: Time for a Redefinition published in The Canadian Medical Association Journal: (1)

“In medicine, the male has been viewed as normative in research, treatment, societal constructs and, until recently, health care provision. Most of us are aware that much of the published medical research has involved male subjects only.”

Perhaps the best-known example of such research – what Dr. Simkin in fact describes as “the height of ludicrousness” – was the 1986 study at New York City’s Rockefeller University on breast and uterine cancer.

Despite the clearly obvious reality of these malignancies in women, all of the subjects in this study were men. Continue reading

Ethicists demand external, independent investigation of Dan Markingson’s death

In November 2003, psychiatrists at the University of Minnesota used the threat of involuntary commitment to force a mentally ill young man named Dan Markingson into a profitable, industry-funded study of antipsychotic drugs. Dan, who was mentally incapable of giving informed consent to participate in this research, was recruited into the study over the objections of his mother, Mary Weiss.

For months Mary tried desperately to get him out of the clinical trials, warning the psychiatrists in writing that Dan’s condition was deteriorating and that he was in danger of killing himself.

The psychiatrists refused to listen to her.

On May 8, 2004, Dan committed suicide, and Mary Weiss lost her only child.  Continue reading

“Heads they win, tails we lose”: the corruption of science

It’s 2003. The American Academy of Pediatric Dentistry accepts a $1 million donation from Coca-Cola. That same year, the group announces  that scientific evidence is certainly not clear on the exact role that soft drinks play in terms of children’s oral disease.”  This statement, according to a report from the Center for Science in the Public Interest, directly contradicts the AAPD’s previous stance: Consumption of sugars in any beverage can be a significant factor that contributes to the initiation and progression of dental caries.”

Yes, I guess it could be purely coincidental that the AAPD decided to contradict what every parent with even a tiny shred of common sense already knows – at the very same time they’ve just inked the $1 million Coca-Cola deal.

But really? Seriously?  Continue reading

What medical researchers mean when they say ____

Just because a scientific paper sounds authoritative, it doesn’t mean we should always take what’s published in journals as gospel. For example, here’s what scientists might really mean when they pontificate:

“It has long been known” . . . [I didn’t look up the original reference]

“A definite trend is evident” . . . [These data are practically meaningless]

“Of great theoretical and practical importance” . . . [Interesting to me]   Continue reading

Aspartame is bad – oops, never mind!

Well, that was embarrassing, wasn’t it? The prestigious Harvard teaching facility Brigham and Women’s Hospital had to apologize for its study suggesting a potential cancer risk from consuming the artificial sweetener aspartame.

In fact, BWH even admitted that their research on this risk was “weak”. Ooops.   Continue reading

The tarnished reputation of university research

As merely a dull-witted heart attack survivor with a relatively recent interest in scientific research (and only because it can influence how my doctor and yours practice medicine), I like to think that university researchers are a noble lot. But in an essay called The Dawn of McScience, Dr. Richard Horton delivers a surprising indictment of academic research.

In his New York Review of Books column about the book called Science in the Private Interest, he cites its author Dr. Sheldon Krimsky of Tufts University School of Medicine, who lumps universities in with industry like so:

“Universities have become little more than instruments of wealth.

“This shift in the mission of academia works against the public interest. Universities have sacrificed their larger social responsibilities to accommodate a new purpose – the privatization of knowledge – by engaging in multimillion-dollar contracts with industries that demand the rights to negotiate licenses from any subsequent discovery.”  Continue reading