“Punytive” damages: the biggest corporate fines ever

Since I’ve discovered the website called Information is Beautiful, I’m afraid that all my available free time for at least the next year or so will be consumed by pouring over this fascinating time-sucker of a site. The book of the same name has been published across the world in nine languages. All of it was conceived and designed by David McCandless, a London-based author, information designer and data journalist. As he explains:

“I’m into anything strange and interesting. A passion of mine is visualizing information – facts, data, ideas, subjects, issues, statistics, questions – all with the minimum of words. Love pie – hate pie-charts.”   Continue reading

Ethicists demand external, independent investigation of Dan Markingson’s death

In November 2003, psychiatrists at the University of Minnesota used the threat of involuntary commitment to force a mentally ill young man named Dan Markingson into a profitable, industry-funded study of antipsychotic drugs. Dan, who was mentally incapable of giving informed consent to participate in this research, was recruited into the study over the objections of his mother, Mary Weiss.

For months Mary tried desperately to get him out of the clinical trials, warning the psychiatrists in writing that Dan’s condition was deteriorating and that he was in danger of killing himself.

The psychiatrists refused to listen to her.

On May 8, 2004, Dan committed suicide, and Mary Weiss lost her only child.  Continue reading

Avandia: a very short history of a very bad drug

The drug giant GlaxoSmithKline’s controversial diabetes drug Avandia (generic name rosiglitazone) works by helping diabetics balance their blood-sugar levels. But since its inception, it has been found to increase the risk of heart attacks and strokes — and even death.

As many as 100,000 heart attacks, strokes, deaths and cases of heart failure may be directly attributed to Avandia since the drug was launched in 1999, according to FDA scientist Dr. David Graham.  Yet physicians are still prescribing the drug to nearly half a million people, which translates into approximately $900 million in annual sales for GSK.  How has this been allowed to happen? Let’s take a look at the history of this potentially lethal but still-legal drug, courtesy of PBS: Continue reading

How other doctors (not you) are influenced by Big Pharma

The pharmaceutical industry spends billions of dollars each year on handing out free samples of their expensive brand name drugs to physicians, who in turn hand them out to their patients.  As I’ve written about here and here, the obvious marketing truth is that no company would be doing this unless the strategy resulted in a significant increase in sales of those drugs.  When you’re looking at a global market for pharmaceuticals expected to top $1.1 trillion by 2014, that’s a substantial incentive to keep up this practice. Still, very few physicians believe that doctors accepting billions of dollars in free drug samples annually has the slightest bit of influence on the way they practice medicine. Except, of course, when it’s those other docs out there who are accepting the freebies.  Continue reading