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Mice are th TOP model organisms for GOOD REASON. Scientists call them furry humans.

All of you Internet cranks are the same. You abuse genuine science.

There are VAST OCEANS of unknowns about obesity and considerable uncertainty. What we know is but a glass of water.

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“The fact that it has such negative press means to me that there is something positive there” – Dr. Ruth, you would not likely say that about Vioxx or other drugs with similarly “negative press”.

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I agree with you completely about the multi-factional ingredients towards obesity. I know from personal experience that taking in too many calories doesn’t make a person obese. I lived for 60 years while overeating. I’m not exactly proud of that—-however it’s a fact. I’m not the only person I know like that.

At the same time I abhor the ads on TV and elsewhere. Especially the lobbying!

So, conversely, an obese person doesn’t necessarily have to be gorging on sweets or fats to remain obese. It’s much more complicated— as you said. Endocrine? Possibly. Or something we’ve never heard of before.

For a peek at what the lobbying expenditures are for recent years go to:
http://www.opensecrets.org/lobby/indusclient.php?id=H04&year=a

Lobbying against more healthy school lunches:

“The food industry and the Congress members it lobbies have apparently reached an agreement on childhood obesity: It’s less important than profit.”
http://tinyurl.com/6sbjdvm

Lobbying against diet pills—– I’d have to read more about that. Could it be that some of the diet pills need more testing? Do you have any citations you can bring forth for me? Although I’m inclined not to trust lobbyists. Sorry.

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How’s this?
If my leptin score had been high (back then) AND there was something that could have been done AND I was overweight—-
I would have tried almost anything that was safe.

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If they were WNL I would’ve kept on eating what I wanted. Remember I had 60 glorious years of almost NO health problems and besides not doing anything stupid (rec. drugs or smoking etc) I wouldn’t have changed. I did drink, maybe a leetle too much at times but when I decided to quit, I just quit. Easy peasy.
But if leptin was high, as they are now, and nothing more was known about leptin then (than now) I would do the same as I’m doing now: keeping an eye on the research and waiting for research that can be replicated/proven to possibly make a choice.

Did that answer you—- or have I just muddied the field?

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I think weight issues are one of the most multifactorial health topics there are. You can’t just talk about heredity, or about calories in, calories out, or about this diet vs that diet, or new science discoveries, e.g. leptin, or about this physical activity or that one, or about other health options – there are so many things that feed into the whole topic it is staggering.

Not to mention a huge sugar lobby whose financial interest lies in keeping the population obese! They actually lobby the FDA to prevent promising weight loss meds from coming onto the market. When I first learned about that, it made me physically ill to think people would so disregard other peoples’ health in order to make money. We’re back to money and power, same old, same old.

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