Comments on: Universal cholesterol screening for little kids? https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/ Marketing Ethics for the Easily Swayed Fri, 26 Aug 2016 00:40:50 +0000 hourly 1 http://wordpress.com/ By: Dr. Enrique Gavilán https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/comment-page-1/#comment-42254 Thu, 09 Aug 2012 15:41:55 +0000 http://ethicalnag.org/?p=7761#comment-42254 Petr Skrabanek wrote in his book “The death of human medicine” a priceless passage which masterfully illustrated how we torment with the hammer of cholesterol lowering “evidences”, to the point of losing our head.

“Food faddism is not only an affection of the simple-minded. In a piece-of-mind article in the Journal of the American Medical Association, a cardiologist wrote touchingly about seeing his four-year-old daughter Ariel sneaking to the fridge in order to have some of the ice-cream that her granny had bought. ‘From conversation around the house she knew what foods were high in saturated fat and cholesterol and that they should be avoided’. She felt guilty and her daddy felt guilty about her guilt. He also felt guilty that he had not yet measured her cholesterol, but he consoled himself that ‘there is no uniform agreement among all experts on when to start screening small children’. Poor Ariel!”

Finally they’ve reached a consensus. Non sensus consensus, of course. Consensus, like most of them, harmful.

Poor Ariel, poor children!

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By: Carolyn Thomas https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/comment-page-1/#comment-20891 Sun, 20 Nov 2011 15:56:57 +0000 http://ethicalnag.org/?p=7761#comment-20891 I’m not a statistician either, merely a dull-witted heart attack survivor who three years ago started questioning the fistful of cardiac meds prescribed for me. But if you google ALLHAT criticism, you’ll find a small avalanche of reports questioning this study’s conclusions, too. For example, this from the Canadian Medical Association Journal. “Questioning the Benefits of Statins”:

“What is the point of decreasing the number of “cardiac events” without decreasing overall mortality, when the harm caused by the side effects of statin therapy is factored in? The failure of statins to reduce all-cause mortality clearly supports the call for more effective approaches. Guidelines should reflect this finding, certainly in their recommendations for women.”

Apparently, the ALLHAT research teams were not quite so honest in their conclusions, given the clearly stated outcomes of their study.

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By: cave76 https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/comment-page-1/#comment-20890 Sun, 20 Nov 2011 15:26:50 +0000 http://ethicalnag.org/?p=7761#comment-20890 I must have missed the ‘cherry-picking’ aspect of that ALLHAT article—- thank you. I should know that ALL studies should be analysed more carefully.
You said:
****THESE RESULTS DO NOT ALTER CURRENT CHOLESTEROL TREATMENT GUIDELINES, which are based on a series of other clinical trials with larger cholesterol reductions than that observed in ALLHAT.”

I took that sentence in the study as a CYA statement. That it wasn’t going to step-on ‘someone’s’ toes. What do you think?

Also this sentence: “But both groups showed the same rates of death, heart attack and heart disease.”

Is that based on shoddy statistics? I’m not questioning to be argumentative—– I really want to know, since statistics are definitely not my forte!

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By: Carolyn Thomas https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/comment-page-1/#comment-20889 Sun, 20 Nov 2011 14:52:49 +0000 http://ethicalnag.org/?p=7761#comment-20889 Yes it is – and, sadly for all these children, it will likely succeed.

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By: Carolyn Thomas https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/comment-page-1/#comment-20888 Sun, 20 Nov 2011 14:34:39 +0000 http://ethicalnag.org/?p=7761#comment-20888 Thanks for pointing out that anything published on the Weston Price site should be read with one’s critical thinking hat on. But ALLHAT is a good example of cherry-picking study results (i.e. showed that LDL numbers went down in the group treated with pravastatin – intermediate endpoints – but only a ‘nonsignificant’ difference in disease/mortality rates between the two groups). ALLHAT was also criticized because 30% of its ‘usual care/non-statin’ group actually WERE prescribed statins during the course of the study. (How can you call these people non-statin users when they were taking statins?) Some experts at the time also theorized that the lack of a significant effect of pravastatin on clinical outcomes was because the trial was performed in patients with high blood pressure. And ALLHAT’s questionable conclusions:

“The ALLHAT lipid-lowering treatment study found only a small (nonsignificant) decrease in cardiovascular event rates for pravastatin compared to usual care, and no difference in mortality. But THESE RESULTS DO NOT ALTER CURRENT CHOLESTEROL TREATMENT GUIDELINES, which are based on a series of other clinical trials with larger cholesterol reductions than that observed in ALLHAT.”

In other words, pay no attention to the man behind the curtain . . .

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By: Dr Joe Kosterich https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/comment-page-1/#comment-20868 Sun, 20 Nov 2011 06:52:32 +0000 http://ethicalnag.org/?p=7761#comment-20868 This is all about opening up a new market for statins at a time when the biggest selling one is losing its patent.

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By: Healthy Heart https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/comment-page-1/#comment-20843 Sat, 19 Nov 2011 19:40:14 +0000 http://ethicalnag.org/?p=7761#comment-20843 […] more here: Universal cholesterol screening for little kids? | The Ethical Nag […]

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By: cave76 https://ethicalnag.org/2011/11/19/universal-cholesterol-screening-for-little-kids/comment-page-1/#comment-20834 Sat, 19 Nov 2011 17:07:50 +0000 http://ethicalnag.org/?p=7761#comment-20834 Remember when our acceptable cholesterol levels were much higher than they are now? I do. Were we told that the acceptable level has been lowered because new science showed that it should—– or was it simply to market more drugs?

I know what I think.

The following is from an article at the Weston A. Price web site; a site I’d advise should be read with your critical-thinking hat on. But it does give some hints as to where to go for more reading.

“ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial), the largest North American cholesterol-lowering trial ever, showed that mortality of the treatment group and controls after three or six years was identical. Researchers used data from more than 10,000 participants given cholesterol-lowering drugs and followed them over a period of four years, comparing the use of a statin drug to “usual care,” namely maintaining proper body weight, no smoking, regular exercise, etc., in treating subjects with moderately high levels of LDL-cholesterol. Of the 5170 subjects in the group that received statin drugs, 28 percent lowered their LDL-cholesterol significantly. And of the 5185 usual-care subjects, about 11 percent had a similar drop in LDL. But both groups showed the same rates of death, heart attack and heart disease.”

Also:

“While the evidence relating elevated cholesterol levels to CHD is strong and consistent, clinical trials have not demonstrated that cholesterol-lowering reduces total mortality. Moreover, observational studies show a U-shaped relationship of cholesterol and mortality, with higher mortality rates for persons with cholesterol levels less than 160 mg/dl and greater than 240 mg/dl compared to those in the range 160-240 mg/dl”

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