Comments on: How did this heart drug get approved in the first place? https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/ Marketing Ethics for the Easily Swayed Sun, 03 Dec 2017 09:43:14 +0000 hourly 1 http://wordpress.com/ By: Lucy Storey https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-44356 Tue, 18 Sep 2012 16:28:36 +0000 http://ethicalnag.org/?p=6638#comment-44356 AMEN!!! Couldn’t have said it better myself.

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]]> By: Lucy Storey https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-44354 Tue, 18 Sep 2012 16:24:44 +0000 http://ethicalnag.org/?p=6638#comment-44354 Sounds to me like more of the same. Let’s push this drug through quickly before they notice. Dr. Battiste should be ashamed of himself being bought by the big giants and Johnson & Johnson keeps getting bigger and bigger because they have deep pockets to dangle that carrot in front of the right noses. They are no fools. What happened to honest research to help real people’s needs? The mighty bottom line. MONEY, POWER and GREED.

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]]> By: Carolyn Thomas https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-14791 Thu, 21 Jul 2011 16:34:06 +0000 http://ethicalnag.org/?p=6638#comment-14791 Well, you just know that I do . . . . 😉

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]]> By: Dr. Steve Parker https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-14790 Thu, 21 Jul 2011 16:24:13 +0000 http://ethicalnag.org/?p=6638#comment-14790 I will do experimental research with both of them this evening.. Particularly looking forward to the Scotch. Glad to know there is an antidote for Big Pharma cynicism.

(On the other hand, this could be proof that Big Pharma practices are driving me to drink. Can I sue? Do you know any good law firms that have no scruples that you can recommend?)

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]]> By: Carolyn Thomas https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-14734 Tue, 19 Jul 2011 13:48:09 +0000 http://ethicalnag.org/?p=6638#comment-14734 Well said, Margi. Your excellent questions deserve answers. This study was undertaken, for example, due to years of safety concerns about this drug – which is why J&J’s response is so ludicrous (“…increased our understanding of the drug’s safety profile…”). ?!?!

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]]> By: Margi Macdonald https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-14727 Tue, 19 Jul 2011 05:46:50 +0000 http://ethicalnag.org/?p=6638#comment-14727 Back in the 1980s I was an RN, working in a cardio-thoracic unit. The thing which makes my blood boil – and my spirit despair – when I read this kind of story is that Doctors at the bedside who prescribe drugs such as this, are effectively selling hope and some kind of future to patients who face a potentially life-limiting condition.

Why have Doctors become so trusting and reliant upon the ‘blah blah’ fed to them by Big Pharma and whatever it is we call the checks and balances which should exist in the FDA – and here in Australia, the TGA?

What has become of simple, good ol’ fashioned medical ethics and a healthy dose of scientific caution and skepticism?

I swear, in the past 20 years, the practice of medicine has become some kind of mass-delusional belief system, captivated by so-called innovation, paying homage to the costly and the unique, its adherents in the thrall of the distorted dogma of Evidence-Based Medicine [EBM].The foundation stones of EBM are in fact, the objective experiences and observations of multitudes of individual practitioners, not the meta-analyses of randomly controlled trials [RCTs].

Where are all the cardiologists who administered this drug, and saw no real benefit in the men and women – beloved by others – who received it? Where is their evidence? What were their experiences, and those of their patients? Why has this evidence not been gathered, collated and openly discussed before now? Or if it was, why were those voices unheard and unnoticed?

The meta-analysis of multiple RCTs – merely the pointy tip of the pyramid of evidence – is no tool for revealing truth, safety, or efficacy, and RCT’s are too easily corrupted by slick statistical manipulation, lack of external validity, artfully crafted conclusions which play loosely with the truth, the machinations of Big Pharma and the people in its pay etc etc.

It must surely be time to rethink how we gather medical information [evidence], who should be gathering it, and how this information is used.

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]]> By: Carolyn Thomas https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-14726 Tue, 19 Jul 2011 05:07:09 +0000 http://ethicalnag.org/?p=6638#comment-14726 Personally, I have found that a nice 12-year old Macallan scotch tends to reduce my cynicism. Or a good red wine like an Italian Barolo, which of course has the added benefit of being heart-healthy . . .

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]]> By: Dr. Steve Parker https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-14725 Tue, 19 Jul 2011 04:40:53 +0000 http://ethicalnag.org/?p=6638#comment-14725 Carolyn:

One could become cynical about Big Pharma (and about the FDA).

Cynicism, no doubt, is bad for the heart.

Can you please recommend a drug to reduce cynicism?

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]]> By: Carolyn Thomas https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-14710 Mon, 18 Jul 2011 15:34:22 +0000 http://ethicalnag.org/?p=6638#comment-14710 Hey! Watch your language there, Dr. Joe! 😉

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]]> By: Dr Joe https://ethicalnag.org/2011/07/18/how-did-this-heart-drug-get-approved-in-the-first-place/comment-page-1/#comment-14709 Mon, 18 Jul 2011 14:51:35 +0000 http://ethicalnag.org/?p=6638#comment-14709 Seriously, all I can say is – Goodness Me!

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