Generic drugs: are they really ‘exactly’ the same as brand name drugs?

Joe Graedon, who has been writing about pharmaceuticals for three decades and runs a consumer advocacy website, The People’s Pharmacy , was 100% behind generic drugs for many years. “We were the country’s leading generic enthusiasts,” he told the New York Times in November.  But over the last eight or nine years, Graedon began hearing about “misadventures” from people who read his syndicated newspaper column, also called The People’s Pharmacy.

The stories were typically from patients who were switched from a brand name drug to a generic one, and then had side effects or found that their symptoms returned — or even became worse than before they were medicated.

Most recently, Joe Graedon has been hearing complaints on his website about generic forms of the anti-depressant Wellbutrin XL 300 (known as Budeprion XL 300 in one generic form), the heart medicine Toprol XL (metoprolol succinate) and the anti-seizure medicine Keppra (levetiracetam). His opinion?

“Consumers are told generics are identical to brand name drugs, but that is clearly not always the case.” Continue reading

Why Oprah is not your doctor

Live Your Best Life Ever! Wish Away Cancer! Get A Lunchtime Face-Lift! Eradicate Autism!  Turn Back The Clock!  Thin Your Thighs!  Cure Menopause!  Harness Positive Energy!  Erase Wrinkles!  Banish Obesity! 

Yes, dear little nags-in-training, you can apparently learn how to perform all these miracles just by watching Oprah every day on TV.

In June, Newsweek magazine ran a revealing Oprah overview by Weston Kosova and Pat Wingert called “Why Health Advice on Oprah Could Make You Sick”.

Their observations focused on Oprah guests whose quasi-medical theories – proven or not – the influential talk show host has decided to endorse. One such celebrity guest is of course the age-denying Suzanne Somers, weighing in on the debate about hormone replacement for menopausal women. The Newsweek piece said:

“Outside Oprah’s world, there isn’t a raging debate about replacing hormones. Women just don’t need as much once they get past their childbearing years. Unless a woman has significant discomfort from hot flashes—and most women don’t—there is little reason to prescribe them. Most women don’t use them. Hormone therapy can increase a woman’s risk of heart attacks, strokes, blood clots and cancer.

And despite Somers’ claim that her specially made, non-FDA-approved bio-identicals are ‘natural’ and safer, they are actually synthetic, just like conventional hormones and FDA-approved bio-identicals from pharmacies.  There are no conclusive clinical studies showing hers are less risky. That’s why endocrinologists advise that women take the smallest dose that alleviates symptoms, and use them only as long as they’re needed.” Continue reading

Sock puppetry, astroturfing, and the marketing ‘shill’ game

The American plastic surgery company called Lifestyle Lift allegedly ordered employees in 32 centres to post fake positive reviews online about their $5,000 quickie facelift procedure.  But last summer, New York Attorney General Andrew Cuomo stepped in, investigated the company for fraud, and ordered Lifestyle Lift to pay $300,000 in penalties (which is roughly equivalent to lunch money for the cosmetic surgeons).

The attorney general’s office said the case is believed to be the first in the U.S. addressing a form of ‘stealth marketing’ called astroturfing.

Astroturfing refers to political, advertising, or public relations campaigns that are formally planned by an organization or company, but designed to mask their true origins to create the impression of being spontaneous, popular “grassroots” behaviour. (The term refers to AstroTurf, a brand of synthetic carpeting designed to look like natural grass).  Astroturfing campaigns are widely considered by us PR types to be behind the growing trend towards noisy health care protests and town hall meetings in the U.S.

William Greider’s 1992 book, Who Will Tell the People, described a typical astroturf campaign run by Bonner & Associates in this way:

“It was a ‘boiler room’ operation with 300 phone lines and a sophisticated computer system, resembling the phone banks employed in election campaigns. Articulate young people sit in little booths every day, dialing around the country on a variety of public issues, searching for ‘white hat’ citizens who can be persuaded to endorse the political objectives of Mobil Oil, Dow Chemical, Miller Brewing, United States Tobacco Company, the Chemical Manufacturers Association, the Pharmaceutical Manufacturers Association and dozens of other clients.”  

In online astroturfing, employees like those at Lifestyle Lift pose as independent consumers to post positive web reviews about their own company.

Cuomo’s office said these phoney reviews

“ …constitute deceptive commercial practices, false advertising and fraudulent and illegal conduct under New York and federal consumer protection law.” 

Besides the cash penalty, Lifestyle Lift was ordered to stop publishing anonymous positive reviews online.

An astonishingly stupid press release issued by the company responded:

“Lifestyle Lift regrets that earlier third-party website content did not always properly reflect and acknowledge patient comments, or always admit the content was by Lifestyle Lift.”

I don’t know about you, but I do not think I would want my cosmetic surgery performed by somebody who is astonishingly stupid.  Continue reading

Bioethical journal: “How drug marketing corrupts every part of the scientific and medical network”

When a psychiatrist stands up and blasts Big Pharma, you know something is very wrong. This happened recently with the publication of an Australian study exposing corrupt drug company marketing practices, including covering up adverse side effects and pushing patients on to new, more expensive drugs even when those are less effective. Adelaide psychiatrist Dr. Peter Parry and his American colleague Dr. Glen Spielmans reported in the Journal of Bioethical Inquiry:

“Drug marketing is a very sophisticated system which corrupts every part of the scientific and medical network.  Science has largely been taken captive in the name of increasing profits for pharmaceutical firms.”

Parry and Spielmans defend this shocking assessment by pointing to over 400 internal documents obtained from U.S. and European drug companies for this study. Continue reading